Siemens Senior Biochemist - Antibody Purification/ Protein Development in Elkhart, Indiana

Senior Biochemist - Antibody Purification/ Protein Development

Locations:Elkhart, Indiana

Job Family: Research & Development

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Job Description

Division: Siemens Healthineers

Business Unit: Laboratory Diagnostics

Requisition Number: 229979

Primary Location: United States-Indiana-Elkhart

Assignment Category: Full-time regular

Experience Level: Mid level

Education Required Level: Bachelor's Degree

Travel Required: 5%

Division Description:

At Siemens Healthineers, we are passionate about enabling healthcare professionals to deliver high quality patient care, and to do so affordably. A leading global healthcare company, Siemens Healthineers continues to strengthen our portfolio of medical imaging and laboratory diagnostics, while adding new offerings such as managed services, consulting, and healthcare IT services – as well as further technologies in the growing market for therapeutic and molecular diagnostics.

Siemens Healthineers develops innovations that support better patient outcomes with greater efficiencies, giving providers the confidence they need to meet the clinical, operational and financial challenges of a changing healthcare landscape.

Job Description:

Position Overview

This Sr. Biochemist position is in a group that provides mammalian cell culture materials and ascites for antibody purification to support reagent manufacturing for in-vitro diagnostics. The candidate will employ various cell culture methods to grow hybridoma cells for ascites production, set up and run bioreactors up to 500L scale. The candidate will use ELISA and various gel techniques to qualify materials for downstream processing. In addition, different filtration methods and tangential flow filtration method will be used to clarify and concentrate large scale bioreactor harvests prior to antibody purification.

Responsibilities

  • Employs various techniques for growing mammalian cell cultures

  • Operates, maintains, and troubleshoots different size bioreactor equipment.

  • Completes production documentation in an accurate and expedient manner aligned with cGDP practices.

  • Develops protocols and performs qualification of new equipment for use in manufacturing.

  • Completes feasibility studies, writes feasibility reports and prepares qualification paperwork for process scale-up to support increasing manufacturing demands.

  • Troubleshoots and resolves complex problems

Required Knowledge/Skills, Education, and Experience

  • B.S. in biology, chemistry or related discipline. Master/Doctoral degree or equivalent industrial experience is preferred.

  • Knowledge of GMP/ISO is a plus.

  • Proven good writing and laboratory skills.

  • Demonstrated ability to interpret data and to troubleshoot and resolvetechnical issues.

  • The successful candidate will be proficient in time management, possess well developed interpersonal skills, demonstrate strong written and verbal communication skills, and exhibit attention to detail.

Qualified Applicants must be legally authorized for employment in the Unites States. Qualified Applicants will not require employer sponsored work authorization now or in the future for employment in the United States.

Equal Employment Opportunity Statement

Siemens is an Equal Opportunity and Affirmative Action Employer encouraging diversity in the workplace. All qualified applicants will receive consideration for employment without regard to their race, color, creed, religion, national origin, citizenship status, ancestry, sex, age, physical or mental disability, marital status, family responsibilities, pregnancy, genetic information, sexual orientation, gender expression, gender identity, transgender, sex stereotyping, protected veteran or military status, and other categories protected by federal, state or local law.

EEO is the Law

Applicants and employees are protected under Federal law from discrimination. To learn more, Click here at https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm .

Pay Transparency Non-Discrimination Provision

Siemens follows Executive Order 11246, including the Pay Transparency Nondiscrimination Provision. To learn more, Click here at https://www.dol.gov/ofccp/pdf/pay-transp_formattedESQA508c.pdf .